- High-Potency Enzyme Combination for Digestion of Food Protein
- High Dipeptidyl Peptidase IV (DPP IV) Activity Without Papain
- Increases Breakdown of Casein, Gluten, Soy Protein
- Odorless and Tasteless Version of Original Peptizyde™
- Safe, Non-Toxic Alternative or Supplement to GFCF Diet
AFP Peptizyde™ was developed in response to customer requests for a high DPP IV-containing enzyme product that did not include fruit-based enzymes such as papain or bromelain. Like Peptizyde™ (which does contain papain), it is a combination of three different proteolytic enzymes isolated from fungal plant sources. Each enzyme has a unique set of peptide bonds it prefers to break, so the combination of these enzymes allows much more efficient means of quickly and thoroughly breaking down (hydrolyzing) proteins to its smaller components. The enzymes in AFP Peptizyde™ work only on food proteins, not carbohydrates, fats, or other compounds, and do not interfere with medications or other supplements (unless they are also proteins, which is extremely unlikely). AFP Peptizyde™ may be used in combination with other enzyme products, such as Zyme Prime, No-Fenol or other enzyme products. If undecided as to use Peptizyde or AFP Peptizyde™, opt for AFP Peptizyde due to it having no odor/taste or papain.
The aminopeptidase enzyme dipeptidyl peptidase IV, or DPP IV, is able to hydrolyze and inactivate the exorphin peptide, casomorphin and is present in both Peptizyde and AFP Peptizyde. However, for maximal protein breakdown, DPP IV is not useful alone, and should be combined with other proteases with different and less stringent peptide bond specificity. For this reason, AFP Peptizyde™ contains two other fungal proteases with high activity in acid conditions. These enzymes are present in AFP Peptizyde™ in high amounts for the purpose of quickly hydrolyzing proteins while the food is still in the stomach. The ability of AFP Peptizyde™ enzymes to withstand the low pH of the stomach and remain active under acidic conditions allows hydrolysis of casein and gluten prior to entrance into the small intestine. Casein and gluten, in the presence of pancreatic enzymes in the duodenum, can produce exorphin peptides that may be readily absorbed from the intestine (these peptides are not absorbed from the stomach). AFP Peptizyde™ supplements the "normal" hydrolysis of casein, gluten, and other food proteins such that the exorphin peptides are not produced because the specific cleavage pattern to produce these peptides is altered.
AFP Peptizyde™ is similar to Peptizyde™ in that it also contains only those enzymes needed for protein hydrolysis. No other enzymes have been added. An advantage to this approach is that less potential exists for intolerance reactions due to additional and perhaps unnecessary enzyme proteins. Also, by using only three enzyme blends in AFP Peptizyde™, larger amounts of each enzyme can be added per capsule, insuring that more hydrolysis of food protein can take place in the short time that food is in the stomach.
AFP Peptizyde is recommended for high protein diets and athletic training; and dosing may be increased for those meals that are higher in meat protein.
Contraindications for Enzyme Supplementation
These enzymes should NOT be used under the following circumstances: active stomach or duodenal ulcers, severe bowel inflammation (characterized by blood in stools), hemophilia and other bleeding disorders, or within a week of scheduled surgery. This product may not be appropriate for those with known allergies to Aspergillus enzyme proteins, though non-specific mold allergies do not necessarily preclude use of fungal enzymes. Consult your medical doctor for further advice, and err on the side of caution. Those with known anaphylactic allergic reactions to fungal proteins should NOT ingest fungal-derived enzymes.
For those using Peptizyde™ successfully, there is no need to change to AFP Peptizyde™. AFP Peptizyde™ was designed for those who could not tolerate the original Peptizyde™ formulation.
Peptizyde™ is a trademark of Houston Nutraceuticals, Inc.
These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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